4.7 Article

Multi-Gram Scale Synthesis of FR180204

Journal

JOURNAL OF ORGANIC CHEMISTRY
Volume 74, Issue 22, Pages 8870-8873

Publisher

AMER CHEMICAL SOC
DOI: 10.1021/jo901835m

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Funding

  1. Intramural NIH HHS [Z99 HG999999] Funding Source: Medline

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A concise synthesis of the ERK inhibitor FR180204 has been developed. The synthesis consists of six operationally simple steps and can be utilized to make multi-gram quantities of FR180204.

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