Journal
JOURNAL OF ORGANIC CHEMISTRY
Volume 74, Issue 21, Pages 8476-8479Publisher
AMER CHEMICAL SOC
DOI: 10.1021/jo901809k
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Funding
- Deutsche Forschungsgemeinschaft (DFG) [SFB 749]
- Fonds der chemischen Industrie
- Center for Integrated Protein Science Munich CIPS(TM)
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Selective release of enriched biomolecules from solid support is a desirable goal in proteomic and metabolomic studies. Here we demonstrate that photocleavage of a light-sensitive phenacyl ester bond is a suitable alternative cleavage strategy for the selective release of enriched biomolecules form avidin beads circumventing the disadvantages of conventional heat denaturation procedures.
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