4.7 Article

One-Pot Synthesis of Imines and Secondary Amines by Pd-Catalyzed Coupling of Benzyl Alcohols and Primary Amines

Journal

JOURNAL OF ORGANIC CHEMISTRY
Volume 74, Issue 7, Pages 2877-2879

Publisher

AMER CHEMICAL SOC
DOI: 10.1021/jo8026609

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Funding

  1. Korea Research Foundation [KRF-2008-314-C00203]
  2. Pohang Iron & Steal Co., Ltd. (POSCO)
  3. Korean Ministry of Education
  4. National Research Foundation of Korea [2008-314-C00203] Funding Source: Korea Institute of Science & Technology Information (KISTI), National Science & Technology Information Service (NTIS)

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Imines and secondary amines were synthesized selectively by controlling reaction conditions for the Pd-catalyzed one-pot reactions of benzyl alcohols with primary amines. The reactions did not require any additives and were effective for a wide range of alcohols and amines.

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