CuI Nanoparticles for C-N and C-O Cross Coupling of Heterocyclic Amines and Phenols with Chlorobenzenes

Employing CuI nanoparticles as an efficient catalyst for the cross-coupling reactions of various N/O nucleophilic reagents with aryl chlorides could be successfully carried out under mild conditions in the absence of both the ligands and strong bases. A variety of products including N-arylimidazoles and aryl ethers were synthesized in good to excellent yields.