Journal
JOURNAL OF ORGANIC CHEMISTRY
Volume 74, Issue 4, Pages 1730-1732Publisher
AMER CHEMICAL SOC
DOI: 10.1021/jo802350f
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Funding
- Programme Albetaan
- European Union Program of High Level Scholarships for Latin America [E07D402519AR]
- Principado de Asturias
- Spanish Ministerio de Ciencia e Innovacion [CTQ2007-61126/PPQ]
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A novel one-pot tandem biohydrogen transfer process to concurrently obtain two enantiopure sec-alcohols is presented; thus, using a suitable single enzyme and a catalytic amount of cofactor, several interesting building blocks could be easily achieved in an enantiocomplementary fashion, minimizing dramatically the quantity of reagents usually employed in the coupled-substrate approach.
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