4.7 Article

Stereoselective One-Pot, Three-Component Synthesis of 4-Aryltetrahydropyran via Prins-Friedel-Crafts Reaction

Journal

JOURNAL OF ORGANIC CHEMISTRY
Volume 74, Issue 6, Pages 2605-2608

Publisher

AMER CHEMICAL SOC
DOI: 10.1021/jo802531h

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Funding

  1. Department of Science and Technology (DST), New Delhi [SR/S1/OC-33/2007]
  2. Council of Scientific & Industrial Research (CSIR)

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A diastereoselective one-pot, three-component Prins-Friedel-Crafts reaction was developed for the synthesis of 4-aryltetrahydropyran derivatives from the reaction of carbonyl Compounds with homoallylic alcohol in the presence of arene promoted by boron trifluoride etherate.

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