Journal
JOURNAL OF ORGANIC CHEMISTRY
Volume 74, Issue 19, Pages 7574-7576Publisher
AMER CHEMICAL SOC
DOI: 10.1021/jo901552k
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A mild, high-yielding procedure for the preparation of beta-ketophosphonates is described. The condensation is general with respect to the ester and phosphonate, and the products are obtained in high yields within minutes at 0 degrees C. The reaction procedure is operationally simple and amenable to large-scale preparations.
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