Journal
JOURNAL OF ORGANIC CHEMISTRY
Volume 74, Issue 23, Pages 9140-9151Publisher
AMER CHEMICAL SOC
DOI: 10.1021/jo9018705
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Funding
- University of British Columbia
- Canada Research Chair Program
- CH
- BCKDF
- NSERC
- CIHR
- MerckFrosst Canada
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The preparation of 4-carbethoxy-5-methyl-2-(phenylsulfonyl)methyloxizole and Its use in the elaboration of more complex oxazoles are described. A total synthesis of the unique natural products siphonazoles A and B, illustrates an application of this building block. A discussion of the biological activity of the siphonazoles is also presented.
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