Journal
JOURNAL OF ORGANIC CHEMISTRY
Volume 74, Issue 19, Pages 7588-7591Publisher
AMER CHEMICAL SOC
DOI: 10.1021/jo9016748
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- CSIR New Delhi
- DST, New Delhi
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Direct synthesis of condensed triazoles from diverse sulfamidates by ring opening of sulfamidates with sodium azide followed by one-pot propargylation and cycloaddition furnished title compounds. The methodology in general has been demonstrated on diverse sulfamidates derived from amino acids, amino acid derivatives, and carbohydrates to obtain diverse triazole fused scaffolds. In one example, a condensed triazole containing amino acid has been synthesized by ring opening of a sulfamidate derivative with propargyl amine.
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