4.7 Article

AuX3-Mediated Selective Head-to-Head Dimerization of Difluoropropargyl Amides

Journal

JOURNAL OF ORGANIC CHEMISTRY
Volume 74, Issue 20, Pages 7690-7696

Publisher

AMER CHEMICAL SOC
DOI: 10.1021/jo9013436

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Funding

  1. Ministerio de Educacion y Ciencia [CTQ2007-61462]
  2. Ramon y Cajal

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A dimerization of difluoropropargyl amides by reaction with gold(III) halides is described. A reductive elimination of a divinylgold species can be invoked to rationalize its formation. Initial studies of the unusual reactivity of these 1,4-dihalo-1,3-dienes have been performed.

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