4.7 Article

Stereoselective Synthesis of Azetidines and Pyrrolidines from N-tert-Butylsulfonyl(2-aminoalkyl)oxiranes

Journal

JOURNAL OF ORGANIC CHEMISTRY
Volume 74, Issue 20, Pages 7859-7865

Publisher

AMER CHEMICAL SOC
DOI: 10.1021/jo9016666

Keywords

-

Funding

  1. Spanish Ministerio de Educacion y Ciencia [2010-CSD2007-00006, CTQ-2007-65218]

Ask authors/readers for more resources

Base-induced cyclization of enantiopure (2-aminoalkyl)oxiranes allowed the stereospecific formation of pyrrolidin-3-ols and/or 2-(hydroxymethyl)azetidines, depending on the reaction conditions. The oxidation of 2-(hydroxymethyl)azetidines led to azetidine-2-carboxylic acids in high yields.

Authors

I am an author on this paper
Click your name to claim this paper and add it to your profile.

Reviews

Primary Rating

4.7
Not enough ratings

Secondary Ratings

Novelty
-
Significance
-
Scientific rigor
-
Rate this paper

Recommended

No Data Available
No Data Available