Journal
JOURNAL OF ORGANIC CHEMISTRY
Volume 74, Issue 20, Pages 7859-7865Publisher
AMER CHEMICAL SOC
DOI: 10.1021/jo9016666
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Funding
- Spanish Ministerio de Educacion y Ciencia [2010-CSD2007-00006, CTQ-2007-65218]
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Base-induced cyclization of enantiopure (2-aminoalkyl)oxiranes allowed the stereospecific formation of pyrrolidin-3-ols and/or 2-(hydroxymethyl)azetidines, depending on the reaction conditions. The oxidation of 2-(hydroxymethyl)azetidines led to azetidine-2-carboxylic acids in high yields.
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