4.7 Article

Lewis Acid Promoted Carbon-Carbon Double-Bond Formation via Organozinc Reagents and Carbonyl Compounds

Journal

JOURNAL OF ORGANIC CHEMISTRY
Volume 74, Issue 17, Pages 6855-6858

Publisher

AMER CHEMICAL SOC
DOI: 10.1021/jo901252z

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Funding

  1. National Natural Science Foundation of China
  2. Shanghai Municipal Commission of Science and Technology
  3. Shanghai Municipal Commission of Education

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Using cheap and readily available AlCl3 as Lewis acid, functionalized aldehydes react with organozinc reagents to give (E)-alkenes stereoselectively in high yields.

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