Journal
JOURNAL OF ORGANIC CHEMISTRY
Volume 73, Issue 15, Pages 6003-6005Publisher
AMER CHEMICAL SOC
DOI: 10.1021/jo800849d
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Ketones with two bulky substituents, named bulky-bulky ketones, as well as less sterically demanding ketones were successfully reduced to the corresponding optically highly enriched alcohols using a novel identified recombinant short-chain alcohol dehydrogenase RasADH from Ralstonia sp. DSM 6428 overexpressed in E. coli.
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