4.7 Article

Copper-mediated N-cyclopropylation of azoles, amides, and sulfonamides by cyclopropylboronic acid

Journal

JOURNAL OF ORGANIC CHEMISTRY
Volume 73, Issue 16, Pages 6441-6444

Publisher

AMER CHEMICAL SOC
DOI: 10.1021/jo801033y

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Reaction of azoles, amides, and sulfonamides in dichloroethane with readily available cyclopropylboronic acid in the presence of copper acetate and sodium carbonate afforded the N-cyclopropyl derivatives in good to excellent yields.

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