4.7 Article

Highly diastereoselective and enantioselective formal [4+1] ylide annulation for the synthesis of optically active dihydrofurans

Journal

JOURNAL OF ORGANIC CHEMISTRY
Volume 73, Issue 17, Pages 6909-6912

Publisher

AMER CHEMICAL SOC
DOI: 10.1021/jo801135j

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Funding

  1. National Natural Science Foundation of China
  2. Major State Basic Research Development Program [2006CB806105]
  3. The Chinese Academy of Sciences
  4. Science and Technology Commission of Shanghai Municipality

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On the basis of the reactions of camphor-derived sulfur ylide with alpha-ylidene-beta-diketones, highly efficient and selective synthesis of optically active dihydrofurans has been achieved.

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