Journal
JOURNAL OF ORGANIC CHEMISTRY
Volume 73, Issue 13, Pages 5159-5162Publisher
AMER CHEMICAL SOC
DOI: 10.1021/jo8008098
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CuI/L-proline-catalyzed coupling of 2-halotrifluoroacetanilides with pyrrole-2-carboxylate esters in DMSO at 80-90 degrees C followed by in situ hydrolysis at 60 degrees C afforded pyrrolo[1,2-a]quinoxalines. Indole-2-carboxylate esters underwent the same process smoothly to provide the corresponding tetracyclic products.
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