Journal
JOURNAL OF ORGANIC CHEMISTRY
Volume 73, Issue 18, Pages 7255-7259Publisher
AMER CHEMICAL SOC
DOI: 10.1021/jo801096m
Keywords
-
Categories
Funding
- National Institutes of Health [RO1 CA 47135]
- National Science Foundation
- Major Research Instrumentation (MRI) Program
- CHE-0521569
Ask authors/readers for more resources
A reinvestigation of a Fijian collection of Cacospongia mycofijiensis has yielded the known mycothiazole and a novel heterocyclic, CTP-431 (1). Its structure including absolute configuration as 8R,9R,10S,13S was established using NMR data, calculated DFT (13)C chemical shifts and results from X-ray crystallography. It is possible that the tricyclic skeleton of CTP-43 1 (1) is biosynthetically related to the macrolide latrunculin A, however the thiopyrone moiety of 1 has no previous precedent in natural products chemistry.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available