Histomorphometric Analysis of Maxillary Sinus Augmentation Using an Alloplast Bone Substitute

Purpose: To evaluate the regenerative potential of a fully synthesized homogenous hydroxyapatite: beta-tricalcium phosphate 60: 40 alloplast material in sinus lift procedures. Materials and Methods: Hydroxyapatite: beta-tricalcium phosphate was used for sinus floor augmentation. After 9 months, 12 biopsies were taken from 12 patients. Routine histologic processing was performed and specimens were analyzed using a light microscope and a digital camera. Results: Histologic evaluation showed 26.4% newly formed bone, 27.3% residual graft material, and 46.3% bone marrow. The osteoconductive index was 33.5%. Conclusions: Hydroxyapatite: beta-tricalcium phosphate 60: 40 alloplast material was found to be biocompatible and osteoconductive in maxillary sinus augmentation procedures. (C) 2012 Published by Elsevier Inc on behalf of the American Association of Oral and Maxillofacial Surgeons J Oral Maxillofac Surg 70:1835-1843, 2012