Journal
JOURNAL OF OCCUPATIONAL AND ENVIRONMENTAL MEDICINE
Volume 56, Issue 2, Pages 149-154Publisher
LIPPINCOTT WILLIAMS & WILKINS
DOI: 10.1097/JOM.0000000000000089
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Funding
- National Institute of Environmental Health Sciences [ES-09825, ES-00002]
- US Environmental Protection Agency [R826780-01-0, R827353-01-0]
- Ohio Coal Development Office [CDO/D-98-2]
- US Department of Energy's National Energy Technology Laboratory [DE-FC26-00NT40771]
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Objective: We examine whether ambient air pollution is associated with oxygen saturation in 32 elderly subjects in Steubenville, Ohio. Methods: We used linear mixed models to examine the effects of fine particulate matter less than 2.5 m (PM2.5), sulfate (SO42-), elemental carbon, and gases on median oxygen saturation. Results: An interquartile range increase of 13.4 g/m(3) in PM2.5 on the previous day was associated with a decrease of -0.18% (95% confidence interval: -0.31 to -0.06) and a 5.1 g/m(3) interquartile range increase in SO42- on the previous day was associated with a decrease of -0.16% (95% confidence interval: -0.27 to -0.04) in oxygen saturation during the initial 5-minute rest period of the protocol. Conclusions: Increased exposure to air pollution, including the nontraffic pollutant SO42- from industrial sources, led to changes in oxygen saturation that may reflect particle-induced pulmonary inflammatory or vascular responses.
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