4.6 Article

Introduction of β-Carotene-Rich Orange Sweet Potato in Rural Uganda Resulted in Increased Vitamin A Intakes among Children and Women and Improved Vitamin A Status among Children

Journal

JOURNAL OF NUTRITION
Volume 142, Issue 10, Pages 1871-1880

Publisher

OXFORD UNIV PRESS
DOI: 10.3945/jn.111.151829

Keywords

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Funding

  1. Bill and Melinda Gates Foundation for the Reaching End Users Orange-Fleshed Sweet Potato Project
  2. Danish International Development Agency (DANIDA)
  3. Swedish International Development Cooperation Agency (SIDA)
  4. Syngenta Foundation
  5. Department for International Development (DFID, United Kingdom)
  6. United States Agency for International Development (USAID)
  7. World Bank

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Vitamin A deficiency (VAD) persists in Uganda and the consumption of beta-carotenerich orange sweet potato (OSP) may help to alleviate it. Two large-scale, 2-y intervention programs were implemented among Ugandan farmer households to promote the production and consumption of OSP. The programs differed in their inputs during year 2, with one being more intensive (IP) and the other being reduced (RP). A randomized, controlled effectiveness study compared the impact of the IP and RP with a control on OSP and vitamin A intakes among children aged 6-35 mo (n = 265) and 3-5 y (n = 578), and women (n = 573), and (P compared with control on vitamin A status of 3- to 5-y-old children (n = 891) and women (n = 939) with serum retinol <1.05 mu mol/L at baseline. The net OSP intake increased in both the IP and RP groups (P < 0.01), accounting for 44-60% of vitamin A intake at follow-up. The prevalence of inadequate vitamin A intake was reduced in the IP and RP groups compared with controls among children 6-35 mo of age (>30 percentage points) and women (>25 percentage points) (P < 0.01), with no differences between the IP and RP groups of children (P = 0.75) or women (P = 0.17). There was a 9.5 percentage point reduction in prevalence of serum retinol <1.05 mu mol/L for children with complete data on confounding factors (n = 396; P < 0.05). At follow-up, vitamin A intake from OSP was positively associated with vitamin A status (P < 0.05). Introduction of OSP to Ugandan farming households increased vitamin A intakes among children and women and was associated with improved vitamin A status among children. J. Nutr. 142: 1871-1880, 2012.

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