Journal
JOURNAL OF NUTRITION
Volume 141, Issue 6, Pages 1140-1145Publisher
OXFORD UNIV PRESS
DOI: 10.3945/jn.110.135566
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Funding
- Institut de Salud Carlos III-FEDER [RD06/0045/0000, CP06/00100, PI1001407]
- Centro Nacional de Investigaciones Cardiovasculares [CNIC06]
- Valencia Goverment [ACOMP/2011/151]
- Institut de Salud Carlos III [CP 03/00115]
- Health Department of the Catalan Government (Generalitat de Catalunya) [CP 03/00115]
- Generalitat of Catalunya [2005 SGR 00577]
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Ensuring the accuracy of dietary assessment instruments is paramount for interpreting diet-disease relationships. The present study assessed the relative and construct validity of the 14-point Mediterranean Diet Adherence Screener (MEDAS) used in the Prevencion con Dieta Mediterranea (PREDIMED) study, a primary prevention nutrition-intervention trial. A validated FFQ and the MEDAS were administered to 7146 participants of the PREDIMED study. The MEDAS-derived PREDIMED score correlated significantly with the corresponding FFQ PREDIMED score (r = 0.52; intraclass correlation coefficient = 0.51) and in the anticipated directions with the dietary intakes reported on the FFQ. Using Bland Altman's analysis, the average MEDAS Mediterranean diet score estimate was 105% of the FFQ PREDIMED score estimate. Limits of agreement ranged between 57 and 153%. Multiple linear regression analyses revealed that a higher PREDIMED score related directly (P < 0.001) to HDL-cholesterol (HDL-C) and inversely (P < 0.038) to BMI, waist circumference, TG, the TG:HDL-C ratio, fasting glucose, and the cholesterol:HDL-C ratio. The 10-y estimated coronary artery disease risk decreased as the PREDIMED score increased (P < 0.001). The MEDAS is a valid instrument for rapid estimation of adherence to the Mediterranean diet and may be useful in clinical practice. J. Nutr. 141: 1140-1145, 2011.
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