Journal
JOURNAL OF NUCLEAR MEDICINE
Volume 50, Issue 2, Pages 171-174Publisher
SOC NUCLEAR MEDICINE INC
DOI: 10.2967/jnumed.108.053546
Keywords
molecular imaging; MRI; magnetic cellular tagging; immune cells; stem cells
Funding
- Intramural Research Program of the Clinical Center at the National Institutes of Health
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Transplantation of stem cells or immune cells has shown promise for the treatment of several diseases. Monitoring magnetically la beled cells with MRI has furthered our understanding of cellular migration and the pathophysiology of diseases in experimental models. These studies should pave the way for guiding clinical trials using cell-based therapies. This review briefly describes the various methods used to label and track cells with MRI and the potential for such methods to translate to human applications.
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