Journal
JOURNAL OF NUCLEAR MEDICINE
Volume 51, Issue 1, Pages 1-4Publisher
SOC NUCLEAR MEDICINE INC
DOI: 10.2967/jnumed.109.065680
Keywords
neuroinflammation; microglia; blood-brain barrier; cell tracking; positron emission tomography; peripheral benzodiazepine receptor
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Inflammatory responses are closely associated with many neurologic disorders and influence their outcome. In vivo imaging can document events accompanying neuroinflammation, such as changes in blood flow, vascular permeability, tightness of the blood-to-brain barrier, local metabolic activity, and expression of specific molecular targets. Here, we briefly review current methods for imaging neuroinflammation, with special emphasis on nuclear imaging techniques.
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