Journal
JOURNAL OF NUCLEAR MEDICINE
Volume 49, Issue -, Pages 43S-63SPublisher
SOC NUCLEAR MEDICINE INC
DOI: 10.2967/jnumed.107.045930
Keywords
glucose metabolism; amino acid metabolism; lipid metabolism; PET; optical imaging; MRI
Ask authors/readers for more resources
Molecular imaging of tumor metabolism has gained considerable interest, since preclinical studies have indicated a close relationship between the activation of various oncogenes and alterations of cellular metabolism. Furthermore, several clinical trials have shown that metabolic imaging can significantly impact patient management by improving tumor staging, restaging, radiation treatment planning, and monitoring of tumor response to therapy. In this review, we summarize recent data on the molecular mechanisms underlying the increased metabolic activity of cancer cells and discuss imaging techniques for studies of tumor glucose, lipid, and amino acid metabolism.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available