Journal
JOURNAL OF NUCLEAR CARDIOLOGY
Volume 19, Issue 5, Pages 1044-1059Publisher
SPRINGER
DOI: 10.1007/s12350-012-9588-8
Keywords
PET imaging; ischemia; myocardial; myocardial perfusion imaging: PET
Funding
- Academy of Finland Centre of Excellence in Molecular Imaging in Cardiovascular and Metabolic Research, Helsinki, Finland
- Finnish Foundation for Cardiovascular Research
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Positron emission tomography (PET) enables quantitative measurements of myocardial blood flow (MBF) and myocardial flow reserve (MFR). Recent developments and improved availability of PET technology have resulted in growing interest in translation of quantitative flow analysis from mainly a research tool to routine clinical practice. Quantitative PET measurements of absolute MBF and MFR have potential to improve accuracy of myocardial perfusion imaging in diagnosis of multivessel coronary artery disease as well as definition of the extent and functional importance of stenoses. This article reviews recent advances and experience in the quantitative myocardial perfusion imaging together with issues that need to be resolved for quantitative analysis to become clinical reality.
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