Journal
JOURNAL OF NEUROSURGERY
Volume 110, Issue 2, Pages 229-233Publisher
AMER ASSOC NEUROLOGICAL SURGEONS
DOI: 10.3171/2008.6.17621
Keywords
deep brain stimulation; dystonia; globus pallidus internus; parkinsonism
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Funding
- National Institutes of Health [R01 NS40902]
- Charles H. and Bertha L. Boothroyd Foundation
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The authors report on a patient with craniocervical dystonia who was treated with bilateral GPi stimulation, with excellent improvement in dystonia but at the cost of stimulation-induced, reversible parkinsonism. Stimulation through ventral contacts resulted in maximal relief of craniocervical dystonia but induced considerable hypophonia, bradykinesia, rigidity, freezing, and impaired postural reflexes. Stimulation through dorsal contacts alleviated parkinsonism, but resulted in the return of dystonia. No stimulation parameters could alleviate the dystonia without inducing parkinsonism over the course of his 4-year follow-up. (DOI: 10.3171/2008.6.17621)
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