Journal
JOURNAL OF NEUROSCIENCE METHODS
Volume 204, Issue 1, Pages 68-81Publisher
ELSEVIER
DOI: 10.1016/j.jneumeth.2011.10.031
Keywords
Multivariate methods; Multimodal fusion; ICA; CCA; PLS; MRI
Categories
Funding
- National Institutes of Health [R01EB 006841, R01EB 005846]
- National Sciences Foundation [1017718, 1016619]
- Direct For Computer & Info Scie & Enginr
- Div Of Information & Intelligent Systems [1016619] Funding Source: National Science Foundation
- Div Of Information & Intelligent Systems
- Direct For Computer & Info Scie & Enginr [1017718] Funding Source: National Science Foundation
Ask authors/readers for more resources
The development of various neuroimaging techniques is rapidly improving the measurements of brain function/structure. However, despite improvements in individual modalities, it is becoming increasingly clear that the most effective research approaches will utilize multi-modal fusion, which takes advantage of the fact that each modality provides a limited view of the brain. The goal of multi-modal fusion is to capitalize on the strength of each modality in a joint analysis, rather than a separate analysis of each. This is a more complicated endeavor that must be approached more carefully and efficient methods should be developed to draw generalized and valid conclusions from high dimensional data with a limited number of subjects. Numerous research efforts have been reported in the field based on various statistical approaches, e.g. independent component analysis (ICA), canonical correlation analysis (CCA) and partial least squares (PLS). In this review paper, we survey a number of multivariate methods appearing in previous multimodal fusion reports, mostly fMRI with other modality, which were performed with or without prior information. A table for comparing optimization assumptions, purpose of the analysis, the need of priors, dimension reduction strategies and input data types is provided, which may serve as a valuable reference that helps readers understand the trade-offs of the 7 methods comprehensively. Finally, we evaluate 3 representative methods via simulation and give some suggestions on how to select an appropriate method based on a given research. (C) 2011 Elsevier B.V. All rights reserved.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available