Journal
JOURNAL OF NEUROSCIENCE
Volume 30, Issue 22, Pages 7466-7472Publisher
SOC NEUROSCIENCE
DOI: 10.1523/JNEUROSCI.0859-10.2010
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Funding
- National Institutes of Health [MH61285, MH68858, MH84051]
- National Institute of Mental Health
- Children's Bureau of the Administration on Children, Youth and Families
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Individuals who experience early adversity, such as child maltreatment, are at heightened risk for a broad array of social and health difficulties. However, little is known about how this behavioral risk is instantiated in the brain. Here we examine a neurobiological contribution to individual differences in human behavior using methodology appropriate for use with pediatric populations paired with an in-depth measure of social behavior. Weshow that alterations in the orbitofrontal cortex among individuals who experienced physical abuse are related to social difficulties. These data suggest a biological mechanism linking early social learning to later behavioral outcomes.
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