Journal
JOURNAL OF NEUROSCIENCE
Volume 30, Issue 47, Pages 16041-16043Publisher
SOC NEUROSCIENCE
DOI: 10.1523/JNEUROSCI.3745-10.2010
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Funding
- National Institute of Neurological Disorders and Stroke
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Insomnia is a common sleep disorder, yet its pathophysiological basis remains poorly understood. Studying a group of 192 patients with focal brainlesions, we show a significant association between insomnia and left dorsomedial prefrontal damage. Our findings are the first to demonstrate a link between insomnia and a discrete locus of brain damage, providing novel insight into the neurobiological mechanisms of sleep maintenance.
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