Journal
JOURNAL OF NEUROSCIENCE
Volume 28, Issue 46, Pages 11825-11829Publisher
SOC NEUROSCIENCE
DOI: 10.1523/JNEUROSCI.3463-08.2008
Keywords
reward; motivation; cognition; dopamine; striatum; serotonin; depression; schizophrenia
Categories
Funding
- National Eye Institute
- United States Public Health Service [MH-067937, R37-MH48404, MH-072647]
Ask authors/readers for more resources
There is a growing awareness that emotion, motivation, and reward values are important determinants of our behavior. The habenula is uniquely positioned both anatomically and functionally to participate in the circuit mediating some forms of emotive decision making. In the last few years there has been a surge of interest in this structure, especially the lateral habenula (LHb). The new studies suggest that the LHb plays a pivotal role in controlling motor and cognitive behaviors by influencing the activity of dopamine and serotonin neurons. Further, dysfunctions of the LHb have also been implicated in psychiatric disorders, such as depression, schizophrenia, and drug-induced psychosis.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available