Journal
JOURNAL OF NEURORADIOLOGY
Volume 36, Issue 3, Pages 138-146Publisher
MASSON EDITEUR
DOI: 10.1016/j.neurad.2008.12.001
Keywords
Fetal magnetic resonance imaging; Cerebral midline malformation; Holoprosencephaly; Rhombencephalosynapsis; Gomez-Lopez-Hernandez Syndrome
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Fetal magnetic resonance imaging (MRI) is a well-established second line imaging modatity in identifying complex pathologies of the central nervous system (CNS), especially when ultrasound (US) findings are equivocal. It may enable an early and precise diagnosis, which is essential in terms of management of pregnancy and pre-, peri- and postnatal care. We present three cases with rare complex midline malformations of the CNS, diagnosed prenatally by fetal MRI. Two cases revealed hotoprosencephaly; one case demonstrated rhombencephalosynapsis. In addition, we reviewed the literature and provide a summary of recent findings regarding cerebral. midline development and discuss the advantages of fetal MRI. (C) 2008 Elsevier Masson SAS. All rights reserved.
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