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Declining expression of neprilysin in Alzheimer disease vasculature: Possible involvement in cerebral amyloid angiopathy
M Carpentier et al.
JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY (2002)
Deposition of Alzheimer's β-amyloid is inversely correlated with P-glycoprotein expression in the brains of elderly non-demented humans
S Vogelgesang et al.
PHARMACOGENETICS (2002)
Aβ42-induced increase in neprilysin is associated with prevention of amyloid plaque formation in vivo
MH Mohajeri et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
Oligomeric and fibrillar species of amyloid-β peptides differentially affect neuronal viability
KN Dahlgren et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
Amyloid-β oligomers:: their production, toxicity and therapeutic inhibition
DM Walsh et al.
BIOCHEMICAL SOCIETY TRANSACTIONS (2002)
Biogenesis and metabolism of Alzheimer's disease Aβ amyloid peptides
G Evin et al.
PEPTIDES (2002)
Aβ-degrading endopeptidase, neprilysin, in mouse brain:: synaptic and axonal localization inversely correlating with Aβ pathology
S Fukami et al.
NEUROSCIENCE RESEARCH (2002)
β-amyloid catabolism:: roles for neprilysin (NEP) and other metallopeptidases?
JA Carson et al.
JOURNAL OF NEUROCHEMISTRY (2002)
Angiotensin-converting enzyme degrades Alzheimer amyloid β-peptide (Aβ);: Retards Aβ aggregation, deposition, fibril formation, and inhibits cytotoxicity.
JG Hu et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
Gene expression profiling of amyloid beta peptide-stimulated human post-mortem brain microglia
DG Walker et al.
NEUROBIOLOGY OF AGING (2001)
Microglial chemotaxis, activation, and phagocytosis of amyloid β-peptide as linked phenomena in Alzheimer's disease
J Rogers et al.
NEUROCHEMISTRY INTERNATIONAL (2001)
Degradation of the Alzheimer's amyloid β peptide by endothelin-converting enzyme
EA Eckman et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
Cortical alterations of angiotensin converting enzyme, angiotensin II and AT1 receptor in Alzheimer's dementia
E Savaskan et al.
NEUROBIOLOGY OF AGING (2001)
Neprilysin degrades both amyloid β peptides 1-40 and 1-42 most rapidly and efficiently among thiorphan- and phosphoramidon-sensitive endopeptidases
K Shirotani et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
Immunohistochemical localization of neprilysin in the human cerebral cortex:: inverse association with vulnerability to amyloid β-protein (Aβ) deposition
H Akiyama et al.
BRAIN RESEARCH (2001)
Metabolic regulation of brain Aβ by neprilysin
N Iwata et al.
SCIENCE (2001)
TGF-β1 promotes microglial amyloid-β clearance and reduces plaque burden in transgenic mice
T Wyss-Coray et al.
NATURE MEDICINE (2001)
β-Amyloid efflux mediated by p-glycoprotein
FC Lam et al.
JOURNAL OF NEUROCHEMISTRY (2001)
Reduced neprilysin in high plaque areas of Alzheimer brain:: a possible relationship to deficient degradation of β-amyloid peptide
K Yasojima et al.
NEUROSCIENCE LETTERS (2001)
Clearance of Alzheimer's amyloid-β1-40 peptide from brain by LDL receptor-related protein-1 at the blood-brain barrier
M Shibata et al.
JOURNAL OF CLINICAL INVESTIGATION (2000)
Degradation of amylin by insulin-degrading enzyme
RG Bennett et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2000)
Prominent cerebral amyloid angiopathy in transgenic mice overexpressing the London mutant of human APP in neurons
J Van Dorpe et al.
AMERICAN JOURNAL OF PATHOLOGY (2000)
Insulin-degrading enzyme exists inside of rat liver peroxisomes and degrades oxidized proteins
M Morita et al.
CELL STRUCTURE AND FUNCTION (2000)
Peripherally administered antibodies against amyloid β-peptide enter the central nervous system and reduce pathology in a mouse model of Alzheimer disease
F Bard et al.
NATURE MEDICINE (2000)
Identification of the major Aβ1-42-degrading catabolic pathway in brain parenchyma:: Suppression leads to biochemical and pathological deposition
N Iwata et al.
NATURE MEDICINE (2000)
Cellular expression of isoforms of endothelin-converting enzyme-1 (ECE-1c, ECE-1b and ECE-1a) and endothelin-converting enzyme-2
AP Davenport et al.
JOURNAL OF CARDIOVASCULAR PHARMACOLOGY (2000)