Journal
JOURNAL OF NEUROLOGY
Volume 255, Issue 6, Pages 828-830Publisher
DR DIETRICH STEINKOPFF VERLAG
DOI: 10.1007/s00415-008-0710-4
Keywords
CLL; leptomeningeal involvement
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Leptomeningeal involvement in patients with CLL is relatively rare and the prognosis is usually considered to be poor. The authors reviewed all CLL patients treated in a tertiary referral center to assess the incidence and outcome of leptomeningeal involvement (LI) in CLL. They found an incidence of 1-2% of LI. Most of the patients with LI had a long-term survival, despite failure to clear the cerebrospinal fluid from tumor cells.
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