Journal
JOURNAL OF NEUROIMMUNOLOGY
Volume 269, Issue 1-2, Pages 90-93Publisher
ELSEVIER
DOI: 10.1016/j.jneuroim.2014.02.005
Keywords
Microglia; Gap junctions; Astrocytes; Oligodendrocytes; Brain injury; Alzheimer's disease
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We investigated whether microglia form gap junctions with themselves, or with astrocytes, oligodendrocytes, or neurons in vivo in normal mouse brains, and in pathological conditions that induce microglial activation - brain injury and a model of Alzheimer's disease. Although microglia are in close physical proximity to glia and neurons, they do not form functional gap junctions under these pathological conditions. (C) 2014 Elsevier B.V. All rights reserved.
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