Journal
JOURNAL OF NEUROIMAGING
Volume 18, Issue 3, Pages 227-236Publisher
WILEY
DOI: 10.1111/j.1552-6569.2007.00180.x
Keywords
neural networks; stroke; recovery; functional imaging; TMS; fMRI; ecological
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Functional imaging is beginning to outline the brain's functional architecture and mechanisms of recovery from injury. I will review primarily the motor-function literature from normal populations, learning trials, stroke recovery, and rehabilitation with a neural network approach that may prove fruitful in further advancing our understanding of brain plasticity in response to focal lesions. A key consideration in this review will be how the development of distributed motor networks might constrain recovery as a function of the altered connectivity between damaged and nondamaged areas. It will be argued that this connectivity is central to both recovery from injury and response to treatment.
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