Related references
Note: Only part of the references are listed.Increased NF-κB signalling up-regulates BACE1 expression and its therapeutic potential in Alzheimer's disease
Chia-Hsiung Chen et al.
INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY (2012)
Alzheimer's Association Report 2011 Alzheimer's disease facts and figures
ALZHEIMERS & DEMENTIA (2011)
NF-κB signaling inhibits ubiquitin carboxyl-terminal hydrolase L1 gene expression
Ruitao Wang et al.
JOURNAL OF NEUROCHEMISTRY (2011)
Proteomic and histochemical analysis of proteins involved in the dying-back-type of axonal degeneration in the gracile axonal dystrophy (gad) mouse
Akiko Goto et al.
NEUROCHEMISTRY INTERNATIONAL (2009)
Positive Reciprocal Regulation of Ubiquitin C-Terminal Hydrolase L1 and β-Catenin/TCF Signaling
Anjali Bheda et al.
PLOS ONE (2009)
TMP21 degradation is mediated by the ubiquitin-proteasome pathway
Shengchun Liu et al.
EUROPEAN JOURNAL OF NEUROSCIENCE (2008)
Reduction in memory in passive avoidance learning, exploratory behaviour and synaptic plasticity in mice with a spontaneous deletion in the ubiquitin C-terminal hydrolase L1 gene
Mikako Sakurai et al.
EUROPEAN JOURNAL OF NEUROSCIENCE (2008)
Ubiquitin carboxyl-terminal hydrolase L1, a novel deubiquitinating enzyme in the vasculature, attenuates NF-κB activation
Yoichi Takami et al.
ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY (2007)
Degradation of nicastrin involves both proteasome and lysosome
Guiqiong He et al.
JOURNAL OF NEUROCHEMISTRY (2007)
Dopaminergic neuronal loss in transgenic mice expressing the Parkinson's disease-associated UCH-L1 193M mutant
Rieko Setsuie et al.
NEUROCHEMISTRY INTERNATIONAL (2007)
Ubiquitin-proteasome pathway mediates degradation of APH-1
Guiqiong He et al.
JOURNAL OF NEUROCHEMISTRY (2006)
Ubiquitin hydrolase Uch-L1 rescues β-amyloid-induced decreases in synaptic function and contextual memory
Bing Gong et al.
CELL (2006)
Increased BACE1 maturation contributes to the pathogenesis of Alzheimer's disease in Down syndrome
Xiulian Sun et al.
FASEB JOURNAL (2006)
BACE2, as a novel APP θ-secretase, is not responsible for the pathogenesis of Alzheimer's disease in Down syndrome
Xiulian Sun et al.
FASEB JOURNAL (2006)
Control of APP processing and Aβ generation level by BACE1 enzymatic activity and transcription
Yu Li et al.
FASEB JOURNAL (2006)
A genomic and functional inventory of deubiquitinating enzymes
SMB Nijman et al.
CELL (2005)
Oxidative modifications and down-regulation of ubiquitin carboxyl-terminal hydrolase L1 associated with idiopathic Parkinson's and Alzheimer's diseases
J Choi et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
Mechanism and function of deubiquitinating enzymes
AY Amerik et al.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH (2004)
Ubiquitin carboxy-terminal hydrolase L1 binds to and stabilizes monoubiquitin in neuron
H Osaka et al.
HUMAN MOLECULAR GENETICS (2003)
The UCH-L1 gene encodes two opposing enzymatic activities that affect α-synuclein degradation and Parkinson's disease susceptibility
YC Liu et al.
CELL (2002)
Proteomic identification of oxidatively modified proteins in Alzheimer's disease brain.: Part II:: dihydropyrimidinase-related protein 2, α-enolase and heat shock cognate 71
A Castegna et al.
JOURNAL OF NEUROCHEMISTRY (2002)
Association studies of multiple candidate genes for Parkinson's disease using single nucleotide polymorphisms
Y Momose et al.
ANNALS OF NEUROLOGY (2002)
Mutant ubiquitin expressed in Alzheimer's disease causes neuronal death
FMS De Vrij et al.
FASEB JOURNAL (2001)
A polymorphic variation of serine to tyrosine at codon 18 in the ubiquitin C-terminal hydrolase-L1 gene is associated with a reduced risk of sporadic Parkinson's disease in a Japanese population
J Satoh et al.
JOURNAL OF THE NEUROLOGICAL SCIENCES (2001)
BACE knockout mice are healthy despite lacking the primary β-secretase activity in brain:: implications for Alzheimer's disease therapeutics
SL Roberds et al.
HUMAN MOLECULAR GENETICS (2001)
A degradation signal located in the C-terminus of p21WAF1/CIP1 is a binding site for the C8 α-subunit of the 20S proteasome
R Touitou et al.
EMBO JOURNAL (2001)
Themes and variations on ubiquitylation
AM Weissman
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2001)
Mice deficient in BACE1, the Alzheimer's β-secretase, have normal phenotype and abolished β-amyloid generation
Y Luo et al.
NATURE NEUROSCIENCE (2001)
BACE1 is the major β-secretase for generation of Aβ peptides by neurons
HB Cai et al.
NATURE NEUROSCIENCE (2001)
Elongin BC complex prevents degradation of von Hippel-Lindau tumor suppressor gene products
AR Schoenfeld et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2000)
Presenilins are required for γ-secretase cleavage of β-APP and transmembrane cleavage of Notch-1
ZH Zhang et al.
NATURE CELL BIOLOGY (2000)
Impaired proteasome function in Alzheimer's disease
JN Keller et al.
JOURNAL OF NEUROCHEMISTRY (2000)
Recognition of the polyubiquitin proteolytic signal
JS Thrower et al.
EMBO JOURNAL (2000)