Journal
JOURNAL OF NEURO-ONCOLOGY
Volume 116, Issue 1, Pages 113-117Publisher
SPRINGER
DOI: 10.1007/s11060-013-1261-9
Keywords
Pregnancy; Transformation; High grade glioma
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Brain tumor growth or progression has been shown to occur in low-grade glial tumors and meningiomas. While progression has been documented in this population, transformation to a more aggressive high-grade glial tumor that can lead to increased morbidity and mortality has not been identified. In this case series, we document transformation from low-grade gliomas to high-grade gliomas (WHO grade III and IV) in young women during pregnancy. We further discuss the possible etiologies of this phenomenon.
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