Journal
JOURNAL OF NEURO-ONCOLOGY
Volume 99, Issue 1, Pages 123-128Publisher
SPRINGER
DOI: 10.1007/s11060-009-0096-x
Keywords
Fibrosarcoma; Chemotherapy; Cyclophosphamide; Imatinib
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Radiation-induced midbrain fibrosarcoma is a rare, highly aggressive tumor, which is associated with poor prognosis. We present the case of a 48-year old man with brainstem fibrosarcoma 20 years following radiation therapy received for a pituitary tumor. We discuss this case in the context of the diagnostic criteria for these tumors, and previous reports of secondary and primary sarcomas of the central nervous system.
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