Journal
PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES
Volume 371, Issue 1685, Pages -Publisher
ROYAL SOC
DOI: 10.1098/rstb.2015.0044
Keywords
neurogenic potential; neural precursors; neural progenitors; asymmetric division; patterning genes; Notch signalling
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Funding
- Biotechnology and Biological Sciences Research Council [BB/F021909/1] Funding Source: researchfish
- BBSRC [BB/F021909/1] Funding Source: UKRI
- Biotechnology and Biological Sciences Research Council [BB/F021909/1] Funding Source: Medline
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Arthropods show considerable variations in early neurogenesis. This includes the pattern of specification, division and movement of neural precursors and progenitors. In all metazoans with nervous systems, including arthropods, conserved genes regulate neurogenesis, which raises the question of how the various morphological mechanisms have emerged and how the same genetic toolkit might generate different morphological outcomes. Here I address this question by comparing neurogenesis across arthropods and show how variations in the regulation and function of the neural genes might explain this phenomenon and how they might have facilitated the evolution of the diverse morphological mechanisms of neurogenesis.
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