Journal
JOURNAL OF NATURAL PRODUCTS
Volume 77, Issue 9, Pages 2037-2043Publisher
AMER CHEMICAL SOC
DOI: 10.1021/np5003687
Keywords
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Funding
- Thailand Research Fund
- Chulalongkorn University through the Royal Golden Jubilee Ph.D. Program [PHD/0009/2553]
- Chulalongkom University Fund (Ratchadaphiseksomphot Endownment Fund)
- Ratchadaphiseksomphot Endowment Fund of Chulalongkorn University [RES560530208-AS]
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Seven new limonoids, namely, xylorumphiins EJ (1-2 and 4-7) and 2-hydroxyxylorumphiin F (3), along with three known derivatives (810), were isolated from the seeds of Xylocarpus rumphii. 2-Hydroxyxylorumphiin F (3) and xylorumphiin I (6) displayed moderate inhibitory activity against nitric oxide production from lipopolysaccharide-activated macrophages with IC50 values of 24.5 and 31.3 mu M, respectively.
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