Journal
JOURNAL OF NATURAL PRODUCTS
Volume 77, Issue 6, Pages 1524-1527Publisher
AMER CHEMICAL SOC
DOI: 10.1021/np500275x
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Funding
- Consiglio Nazionale delle Ricerche of Italy (CNR) [PM 01.020.002]
- PON [00117]
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Two new polyketides of the amphidinol family, amphidinol 18 (wAM18, 1) and its corresponding 7-sulfate derivative (AM19, 2), have been isolated from the MeOH extract of the dinoflagellate Amphidinium carterae. Structure elucidation of the two polyoxygenated molecules has been accomplished by extensive use of spectroscopic and spectrometric techniques. AM18 exhibited antifungal activity against Candida albicans at 9 mu g/mL.
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