4.7 Article

Total Synthesis and Structural Revision of (+)-Cristatumin C

Journal

JOURNAL OF NATURAL PRODUCTS
Volume 77, Issue 2, Pages 421-423

Publisher

AMER CHEMICAL SOC
DOI: 10.1021/np400969u

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Funding

  1. Spanish MINECO [SAF2010-17935-FEDER]
  2. Xunta de Galicia [08CSA052383PR]

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Naturally occurring (+)-cristatumin C, a bis-pyrrolidinoindoline diketopiperazine alkaloid isolated from Eurotium cristatum EN-220, is the 2R, 3R, 11S, 15R, 2'R, 3'R, 11'S, 15'S enantiomer, as confirmed by total synthesis.

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