Journal
JOURNAL OF NATURAL PRODUCTS
Volume 76, Issue 10, Pages 1902-1908Publisher
AMER CHEMICAL SOC
DOI: 10.1021/np400454q
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Funding
- National Science Council of Taiwan [NSC100-2320-B-110-001-MY2]
- Ministry of Education of Taiwan [02C030205]
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Seven novel withanolides, sinubrasolides A-G (1-7), have been isolated from the cultured soft coral Sinularia brassica. The structures of the new metabolites were determined by extensive spectroscopic analyses, and the absolute configuration of 1 was established by X-ray crystallographic analysis. The cytotoxicities of compounds 1-7 against a limited panel of cancer cell lines also were determined.
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