Journal
JOURNAL OF NATURAL PRODUCTS
Volume 76, Issue 10, Pages 1976-1983Publisher
AMER CHEMICAL SOC
DOI: 10.1021/np400638r
Keywords
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Funding
- Natural Science Foundation of China [201072234, 21132009]
- National Science and Technology Project of China [2012ZX09301002-002, 2011ZX09307-002-01]
- PCSIRT [IRT1007]
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Five new diterpenoids (1-5), five new sesquiterpenoids (6-10), and three known compounds (11-13) were isolated from the roots of Illicium majus. Their structures were elucidated by extensive spectroscopic analysis. The absolute configuration of 1 was assigned by X-ray crystallography, whereas those of the 1,2-diol moieties in 3 and 4 were determined using Snatzke's method. The abietane acids 1, 2, 11, 12, and 13 displayed antiviral activity against the Coxsackie B3 virus, with IC50 values of 3.3-51.7 mu M/mL.
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