Journal
JOURNAL OF NATURAL PRODUCTS
Volume 75, Issue 6, Pages 1192-1195Publisher
AMER CHEMICAL SOC
DOI: 10.1021/np2009576
Keywords
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Funding
- MEXT [23102007]
- Grants-in-Aid for Scientific Research [23102007] Funding Source: KAKEN
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Spirastrellolides A (1) and B (3) have been isolated as free acids from a marine sponge Epipolasis sp. collected in the East China Sea. These compounds had been isolated from the Caribbean marine sponge Spirastrella coccinea after conversion to the methyl ester. We examined the cytotoxic activities of 1 and 3 and found that the activities of the free acids are comparable to those of the corresponding methyl esters.
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