Journal
JOURNAL OF NATURAL PRODUCTS
Volume 75, Issue 12, Pages 2069-2075Publisher
AMER CHEMICAL SOC
DOI: 10.1021/np3003673
Keywords
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Funding
- National Research Foundation of Korea
- Korean Government (MEST) [KRF-2012R1A2A06046921, KRF-2012R1A1A2003547]
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Four new phenolic compounds, caesalpiniaphenols A-D (1-4), together with eight known compounds were isolated from Caesalpinia sappan heartwood. The chemical structures were established mainly by NMR, MS, ECD, and Mosher's method. Compounds 4, 5, and 7 showed weak inhibitory activity against the LPS-induced NO production in macrophage RAW264.7 cells with IC50 values of 12.2, 3.5, and 5.7 mu M, respectively.
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