Journal
JOURNAL OF NATURAL PRODUCTS
Volume 74, Issue 5, Pages 1335-1338Publisher
AMER CHEMICAL SOC
DOI: 10.1021/np200041v
Keywords
-
Ask authors/readers for more resources
Three new merosesquiterpenoids, metachromins U, V, and W (1-3), were isolated from a specimen of the marine sponge Thorecta reticulata collected off Hunter Island, Tasmania, Australia. Structures of the new compounds were elucidated through extensive NMR investigations and comparison with literature values. The cytotoxicities of 1-3 were assessed against a panel of human tumor cell lines (SF-268, H460, MCF-7, and HT-29) and a mammalian cell line (CHO-K1). All compounds were found to have 50% growth inhibition activities in the range 2.1-130 mu M, with 2 being the most active (GI(50) 2.1-10 mu M).
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available