Journal
JOURNAL OF NATURAL PRODUCTS
Volume 74, Issue 5, Pages 1073-1078Publisher
AMER CHEMICAL SOC
DOI: 10.1021/np2000254
Keywords
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Funding
- National Basic Research Program of China (973 Program) [2009CB522300]
- Chinese Academy of Sciences [KSCX2-YW-R-202, KSCX2-EW-R-15]
- National Natural Science Foundation of China
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Eight new monoterpenoid indole alkaloids, gardfloramine-9-O-beta-D-glucopyranoside (1), 19(E)-18-demethoxygardfloramine-N(4)oxide (2), gardfloramine-N(4)-oxide (3), 18-demethylgardfloramine (4), 19 (E)-9,18-didemethoxygardneramine (5), 19(E)-11-methoxy-9,18-didemethoxygardneramine (6), 9-demethoxy-18-demethylgardneramine (7), and minfiensine-N(4)-oxide (8), along with six known alkaloids, were isolated from Gardneria ovata. The structures of the new alkaloids were established by means of spectroscopic methods. None of the compounds were cytotoxic to five human cancer cell lines.
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