Journal
JOURNAL OF NATURAL PRODUCTS
Volume 73, Issue 4, Pages 720-723Publisher
AMER CHEMICAL SOC
DOI: 10.1021/np900539j
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The study of the n-butanol extract of the New Caledonian sponge Agelas dendromorpha led to the isolation and identification of three new pyrrole-2-aminoimidazole (P-2-AI) alkaloids, named agelastatins E (3) and F (4) and benzosceptrin C (5), together with 10 known metabolites, agelastatin A (1), agelastatin D(2), sceptrin (6), manzacidin A, tauroacidin a, taurodispacamide A, nortopsentin D, thymine, longamide, and 4,5-dibromopyrrole-2-carboxamide. Their structures were assigned by spectroscopic data interpretation. All the compounds were tested for cytotoxic activity.
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