Journal
JOURNAL OF NATURAL PRODUCTS
Volume 73, Issue 5, Pages 925-934Publisher
AMER CHEMICAL SOC
DOI: 10.1021/np100074r
Keywords
-
Funding
- National Institutes of Health [SO6GM08102]
Ask authors/readers for more resources
Ten new diterpenes, 1-10, having a dolabellane skeleton were isolated from a Colombian gorgonian coral of the genus Eunicea. Their structures, as well as those of known compounds 11-18, were determined on the basis of spectroscopic analysis and, in some instances, by chemical conversion and X-ray crystallographic analysis. The absolute structure of 7 was established by chemical conversion from 11, a co-occurring dolabellane congener of known absolute structure. Most of these diterpenoids showed antimalarial activity against the protozoan parasite Plasmodium falciparum.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available